What is the Best Source of Mesenchymal Stem Cells?

Mesenchymal stem cells (MSCs) are adult stem cells that exhibit promising outcomes in preclinical research for a range of diseases.  The right selection of the source of mesenchymal stem cells (MSC) is critical to the success of regenerative medicine in diverse clinical applications.

The quality and number of MSCs, as well as their source circumstances, might affect the regenerative environment's bioactive molecules that produce growth factors, cytokines, and extracellular vesicles, ultimately affecting the clinical outcome.

In this blog, we’ll explore details such as where these cells are found and what the best source is for getting them.

Where are Mesenchymal Stem Cells (MSCs) found?

Mesenchymal stem cells (MSCs) are found in various parts of the human body. They are as follows:

• Bone Marrow:

This is most of common source of mesenchymal stem cells (MSCs). MSCs are among the immature cells found in the spongy bone marrow, which is located inside the bones.

• Adipose Tissue (Fat Tissue):

Adipose tissue is the tissue in the body that accumulates fat. Mesenchymal stem cells (MSCs) can be extracted from adipose tissue as well. 

• Umbilical Cord Tissue:

Stem cells can be extracted from the baby’s umbilical cord just few minutes after birth, and they are most reliable and best source to collect  mesenchymal stem cells. 

• Placental Tissue:

Placental tissue is another source of mesenchymal stem cells (MSCs). The cells can be extracted and preserved at birth for later use.

• Synovial Fluid: 

The synovial fluid of joints also contains small amounts of mesenchymal stem cells (MSCs). 

• Dental Pulp:

The dental pulp of teeth contains tiny portions of mesenchymal stem cells or MSCs.

What is the Best Source of Mesenchymal Stem Cells?

One potentially useful source of mesenchymal stem cells is the baby’s umbilical cord. It has been demonstrated that stem cells with mesenchymal characteristics seen in umbilical cord blood can differentiate into a variety of cell types, including chondrocytes. 

Besides, a huge number of stem cells can be extracted from cord blood sample, and their viability can be maintained for a long  time.

Umbilical cord-derived MSC (UC-MSC) collection or umbilical cord preservation is noninvasive, reasonably simple, and rarely raises ethical concerns. Other areas of the umbilical cord, including the perivascular tissue, Wharton's jelly, and the cord lining, have also been found to have colonies of stem cells.

Conclusion 

Stem cells can cure several life-threatening diseases, and choosing the right source to collect MSCs is important. Collecting MSCs from adults is time-consuming, given the time constraints. Hence, it is best to bank a baby's stem cell, which is non-invasive, risk-free, and easily available.  Cryoviva can help you in cord blood banking at affordable rates with flexible financing options. Learn more about it today!