Hematopoietic stem cells (HSCs) are found in bone marrow and give rise to two types of stem cells: myeloid and lymphoid. Myeloid cells consist of erythrocytes, platelets, neutrophils, basophils, eosinophils, monocytes/macrophages, and dendritic cells. Lymphoid cells include natural killer cells, B lymphocytes, and T lymphocytes.
Control of Hematopoietic Stem Cells
The niche, or HSC microenvironment in the bone marrow, regulates the balance of differentiation and self-renewal to maintain hematopoietic homeostasis. This mechanism is heavily regulated by transcription factors and cytokines. Individual cytokines can be manipulated to encourage regeneration and recovery of hematopoiesis following chemotherapy. TGFβ, a cytokine, promotes HSC quiescence and self-renewal and affects various cell types throughout the hematopoietic process.Benefits of Hematopoietic Stem Cells
Here’s how hematopoietic stem cells are beneficial:- The Capacity of Regeneration:
- Varieties in Lineage Commitment:
- Rapid Blood Cell Production:
- Myelosuppression Therapeutic Potential:
- Treating Blood Disorders:
- Mechanism of Liver Regeneration:
- Inflammatory Environment in Aging:
Hematopoietic stem cell uses are beneficial, some of which are listed already. The major concerns treated by HSC are blood-related diseases and liver regeneration, but research has proven that the potential of HSC is considerably greater and will remain open in the future.
Bottom Line,
Hematopoietic stem cells from cord blood stem cells are valuable sources for those in need of stem cell therapy. At Cryoviva, we offer state-of-the-art cord blood banking to help parents protect their children from health disorders that can be treated with stem cell therapy. The advanced cryogenic technology ensures that the stem cells are well-preserved and ready for use when needed. Connect with our experts today to schedule an appointment to preserve your baby’s cord blood cells.